Neglected Disease – African Sleeping Sickness: Recent Synthetic and Modeling Advances
Identifieur interne : 000C36 ( Main/Exploration ); précédent : 000C35; suivant : 000C37Neglected Disease – African Sleeping Sickness: Recent Synthetic and Modeling Advances
Auteurs : Sarvesh K. Paliwal [Inde] ; Ankita Narayan Verma [Inde] ; Shailendra Paliwal [Inde]Source :
- Scientia Pharmaceutica [ 0036-8709 ] ; 2011.
Abstract
Human African Trypanosomiasis (HAT) also called sleeping sickness is caused by subspecies of the parasitic hemoflagellate
Url:
DOI: 10.3797/scipharm.1012-08
PubMed: 21886894
PubMed Central: 3163371
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neglected Disease – African Sleeping Sickness: Recent Synthetic and Modeling Advances</title><author><name sortKey="Paliwal, Sarvesh K" sort="Paliwal, Sarvesh K" uniqKey="Paliwal S" first="Sarvesh K." last="Paliwal">Sarvesh K. Paliwal</name><affiliation wicri:level="1"><nlm:aff id="af1-scipharm.2011.79.389"> Banasthali University, Distt-Tonk, 304022, Rajasthan, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea> Banasthali University, Distt-Tonk, 304022, Rajasthan</wicri:regionArea><wicri:noRegion>Rajasthan</wicri:noRegion></affiliation></author><author><name sortKey="Verma, Ankita Narayan" sort="Verma, Ankita Narayan" uniqKey="Verma A" first="Ankita Narayan" last="Verma">Ankita Narayan Verma</name><affiliation wicri:level="1"><nlm:aff id="af1-scipharm.2011.79.389"> Banasthali University, Distt-Tonk, 304022, Rajasthan, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea> Banasthali University, Distt-Tonk, 304022, Rajasthan</wicri:regionArea><wicri:noRegion>Rajasthan</wicri:noRegion></affiliation></author><author><name sortKey="Paliwal, Shailendra" sort="Paliwal, Shailendra" uniqKey="Paliwal S" first="Shailendra" last="Paliwal">Shailendra Paliwal</name><affiliation wicri:level="1"><nlm:aff id="af2-scipharm.2011.79.389"> LLRM medical college, Meerut (U.P.), India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea> LLRM medical college, Meerut (U.P.)</wicri:regionArea><wicri:noRegion>Meerut (U.P.)</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21886894</idno><idno type="pmc">3163371</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163371</idno><idno type="RBID">PMC:3163371</idno><idno type="doi">10.3797/scipharm.1012-08</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">000055</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000055</idno><idno type="wicri:Area/Pmc/Curation">000055</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000055</idno><idno type="wicri:Area/Pmc/Checkpoint">000546</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000546</idno><idno type="wicri:Area/Ncbi/Merge">000236</idno><idno type="wicri:Area/Ncbi/Curation">000236</idno><idno type="wicri:Area/Ncbi/Checkpoint">000236</idno><idno type="wicri:doubleKey">0036-8709:2011:Paliwal S:neglected:disease:african</idno><idno type="wicri:Area/Main/Merge">000C38</idno><idno type="wicri:Area/Main/Curation">000C36</idno><idno type="wicri:Area/Main/Exploration">000C36</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Neglected Disease – African Sleeping Sickness: Recent Synthetic and Modeling Advances</title><author><name sortKey="Paliwal, Sarvesh K" sort="Paliwal, Sarvesh K" uniqKey="Paliwal S" first="Sarvesh K." last="Paliwal">Sarvesh K. Paliwal</name><affiliation wicri:level="1"><nlm:aff id="af1-scipharm.2011.79.389"> Banasthali University, Distt-Tonk, 304022, Rajasthan, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea> Banasthali University, Distt-Tonk, 304022, Rajasthan</wicri:regionArea><wicri:noRegion>Rajasthan</wicri:noRegion></affiliation></author><author><name sortKey="Verma, Ankita Narayan" sort="Verma, Ankita Narayan" uniqKey="Verma A" first="Ankita Narayan" last="Verma">Ankita Narayan Verma</name><affiliation wicri:level="1"><nlm:aff id="af1-scipharm.2011.79.389"> Banasthali University, Distt-Tonk, 304022, Rajasthan, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea> Banasthali University, Distt-Tonk, 304022, Rajasthan</wicri:regionArea><wicri:noRegion>Rajasthan</wicri:noRegion></affiliation></author><author><name sortKey="Paliwal, Shailendra" sort="Paliwal, Shailendra" uniqKey="Paliwal S" first="Shailendra" last="Paliwal">Shailendra Paliwal</name><affiliation wicri:level="1"><nlm:aff id="af2-scipharm.2011.79.389"> LLRM medical college, Meerut (U.P.), India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea> LLRM medical college, Meerut (U.P.)</wicri:regionArea><wicri:noRegion>Meerut (U.P.)</wicri:noRegion></affiliation></author></analytic><series><title level="j">Scientia Pharmaceutica</title><idno type="ISSN">0036-8709</idno><idno type="eISSN">2218-0532</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Human African Trypanosomiasis (HAT) also called sleeping sickness is caused by subspecies of the parasitic hemoflagellate <italic>Trypanosoma brucei</italic> that mostly occurs in sub-Saharan Africa. The current chemotherapy of the human trypanosomiases relies on only six drugs, five of which have been developed more than 30 years ago, have undesirable toxic side effects and most of them show drug-resistance. Though development of new anti-trypanosomal drugs seems to be a priority area research in this area has lagged far behind. The given review mainly focus upon the recent synthetic and computer based approaches made by various research groups for the development of newer anti-trypanosomal analogues which may have improved efficacy and oral bioavailability than the present ones. 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Brussel</name></author><author><name sortKey="Olsen, Jr" uniqKey="Olsen J">JR Olsen</name></author><author><name sortKey="Meints, Ga" uniqKey="Meints G">GA Meints</name></author><author><name sortKey="Burzynska, A" uniqKey="Burzynska A">A Burzynska</name></author><author><name sortKey="Kafarski, P" uniqKey="Kafarski P">P Kafarski</name></author><author><name sortKey="Croft, Sl" uniqKey="Croft S">SL Croft</name></author><author><name sortKey="Oldfield, E" uniqKey="Oldfield E">E Oldfield</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Daunes, S" uniqKey="Daunes S">S Daunes</name></author><author><name sortKey="D Silva, C" uniqKey="D Silva C">C D'Silva</name></author><author><name sortKey="Kendrick, H" uniqKey="Kendrick H">H Kendrick</name></author><author><name sortKey="Yardley, V" uniqKey="Yardley V">V Yardley</name></author><author><name sortKey="Croft, Sl" uniqKey="Croft S">SL Croft</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Paliwal, Sarvesh K" sort="Paliwal, Sarvesh K" uniqKey="Paliwal S" first="Sarvesh K." last="Paliwal">Sarvesh K. Paliwal</name></noRegion><name sortKey="Paliwal, Shailendra" sort="Paliwal, Shailendra" uniqKey="Paliwal S" first="Shailendra" last="Paliwal">Shailendra Paliwal</name><name sortKey="Verma, Ankita Narayan" sort="Verma, Ankita Narayan" uniqKey="Verma A" first="Ankita Narayan" last="Verma">Ankita Narayan Verma</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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